Table 2. Expression probes and DEGs ranked by significance of sex specificity.

Expression probe	Gene symbol	Gene name	Rank by p-value in sex-stratified analysis			Effect size (ratio current/never smokers) in sex-stratified analysis
			Males	Females	p rank difference	Males	Females
A_23_P120883	NMOX1	heme oxygenase (decycling) 1	29,411	31	2.82E-05	1.00	0.77
A_23_P87013	TAGLN	transgelin	29,013	74	3.86E-05	1.00	0.80
A_24_P410453	SYNE1	spectrin repeat containing. nuclear envelope 1	28,573	120	5.42E-05	1.00	0.81
A_23_P23834	LGR6	leucine-rich repeat-containing G protein-coupled receptor 6	27,005	26	1.46E-04	1.49	0.72
A_23_P136347	EPS8	epidermal growth factor receptor pathway substrate 8	26,954	16	1.50E-04	0.99	0.75
A_24_P173754	C1orf21	chromosome 1 open reading frame 21	24,586	24	6.54E-04	0.98	0.78
A_23_P354387	MYOF	myoferlin	24,542	111	7.06E-04	0.98	0.79
A_23_P66881	RGS9	regulator of G-protein signaling 9	21,736	118	3.29E-03	0.96	0.79
A_24_P76644			20,804	121	5.24E-03	0.98	0.88
A_23_P86682	MYOF	myoferlin	19,999	56	7.46E-03	0.96	0.78
A_23_P43679	ZNF618	zinc finger protein 618	19,852	22	7.86E-03	0.96	0.84
A_23_P1962	RARRES3	retinoic acid receptor responder (tazarotene induced) 3	19,775	113	8.49E-03	0.97	0.87
A_23_P113161	C1orf21	chromosome 1 open reading frame 21	19,632	47	8.80E-03	0.95	0.75
A_24_P921823	TCF7L2	transcription factor 7-like 2 (T-cell specific. HMG-box)	18,329	7	1.53E-02	0.96	0.77
A_23_P45831	CHD1L	chromodomain helicase DNA binding protein 1-like	19,187	1,428	1.94E-02	0.98	0.93
A_23_P48175	TMEM106C	transmembrane protein 106C	18,096	410	2.00E-02	0.96	0.88
A_23_P39251	PLIN5	perilipin 5	229	17,725	2.16E-02	1.34	1.05
A_23_P200780	TGFBR3	transforming growth factor. beta receptor III	17,259	94	2.47E-02	0.94	0.80
A_23_P110791	CSF1R	colony stimulating factor 1 receptor	16,516	49	3.23E-02	0.95	0.80
A_32_P140475	KIAA1377	KIAA1377	72	16,014	3.93E-02	0.82	0.97
A_23_P213620	PPP2R2B	protein phosphatase 2. regulatory subunit B. beta	16,049	256	4.14E-02	0.94	0.86
A_32_P75141			15,969	240	4.24E-02	0.94	0.85
A_23_P385105	PLCD4	phospholipase C. delta 4	15,930	354	4.48E-02	0.94	0.86
A_24_P88763	LOXL3	lysyl oxidase-like 3	15,979	413	4.50E-02	0.95	0.89
A_24_P9883	DKFZp761E198	DKFZp761E198 protein	27	15,524	4.61E-02	1.49	1.05
A_23_P109171	BFSP1	beaded filament structural protein 1. filensin	15,892	481	4.75E-02	0.93	0.84