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. 2017 Feb 22;7:41904. doi: 10.1038/srep41904

Table 2. Comparing of pharmacokinetic parameter after adminstration RGD-TRAIL or RGD-TRAIL-ELP to rat at 100 μg (0.5 mg/kg) i.v, n = 4.

Pharmacokinetic parameter RGD-TRAIL RGD-TRAIL-ELP
ACUinfa (ng·min/ml) 139623.75 ± 26170.08 402790 ± 41932.57
T1/2b (min) 50.87 ± 9.14 230.05 ± 11.42
CLc (ml/min) 0.94 ± 0.15 0.26 ± 0.026

aACUinf: Area under the curve from zero to infinity.

bT1/2: Half-life.

cCL: Clearance.