Table 1.

Bioinformatic analysis of whole genome RNAi screen hits.

Ingenuity Canonical Pathwaysa		p-value
1	EIF2 Signaling (6)	0.000098
2	Assembly of RNA Polymerase II Complex (3)	0.0011
3	Cell Cycle: G1/S Checkpoint Regulation (3)	0.0019
4	Glucocorticoid Receptor Signaling (5)	0.0041
5	Nucleotide Excision Repair Pathway (2)	0.0087
6	Notch Signaling (2)	0.010
7	Coenzyme A Biosynthesis (1)	0.012
8	Estrogen Receptor Signaling (3)	0.015
9	Lysine Degradation II (1)	0.020
10	Ceramide Biosynthesis (1)	0.024
11	Oleate Biosynthesis II (Animals) (1)	0.048

^aNumbers in parentheses indicate numbers of RNAi screen hits in each pathway