Table 2.
Staging of concomitant Alzheimer's pathology
| All cases | Brainstem | Limbic | Neocortical | |
|---|---|---|---|---|
| Braak stage | ||||
| 0 | 3 | 1 | 1 | 1 |
| I–II | 30 | 2 | 12 | 16 |
| III–IV | 24 | 1 | 5 | 18 |
| V–VI | 38 | 1 | 9 | 28 |
| Thal phase | ||||
| 0 | 18 | 2 | 10 | 6 |
| 1 or 2 | 4 | 1 | 2 | 1 |
| 3 | 70 | 2 | 15 | 53 |
| 4 or 5 | 3 | 0 | 0 | 3 |
AD pathology including Braak neurofibrillary tangle stage and Thal amyloid phase are indicated for all cases and for each Lewy pathology subtype. While severe tau pathology was most commonly seen across all cases, severe amyloid pathology was seen only in three cases, all of which were neocortical. Alternatively, a lack of tau pathology was seen only in three cases, whereas no amyloid was found in 18 cases, most of which were limbic.