Figure 6.
Brain regions showing increased functional connectivity in the GHRD group than controls at rest. The DMN is the most commonly observed resting-state network associated with internally directed mental states and cognitive function and its coordinated activity diminishes with age (Mevel et al., 2013). The yellow areas indicate the DMN defined by all participants in this study using each seed region. Relative to the control group, the GHRD group had greater functional connectivity in the precuneus (shown in red) with the PCC seed (A), the left hippocampal seed (B), and the right hippocampal seed (C). With the PCC seed region, this group difference was also observed in the left occipital cortex.