Table 3.
General effects of 4EGI-1
| Figure | Variable (number/μm) | Direction of drug effect | Training effect |
Drug effect |
Training × drug |
|||
|---|---|---|---|---|---|---|---|---|
| F | p | F | p | F | p | |||
| Main effect | Main effect | |||||||
| 3B | Sp with no PR, PSD < 0.1 μm2 | ↑ | 0.36 | 0.54842 | 4.21 | 0.04460 | 1.49 | 0.22608 |
| 3B | Sp with no PR, PSD > 0.2 μm2 | ↑ | 0.05 | 0.81632 | 4.47 | 0.03878 | 1.67 | 0.18377 |
| 3C | Sp with base/neck PR, PSD < 0.1 μm2 | ↓ | 0.70 | 0.40561 | 4.91 | 0.03056 | 2.06 | 0.11464 |
| 5B | Sp with SA, no astro, no PR | ↑ | 0.00 | 0.94731 | 5.43 | 0.02329 | 1.83 | 0.15226 |
| Drug group | Box group | |||||||
| 2B | Total PR | ↓ | 3.52 | 0.07098 | 14.19 | 0.00082 | 7.80 | 0.00018 |
| 2C | Shaft PR | ↓ | 2.03 | 0.16502 | 7.12 | 0.01273 | 5.59 | 0.00191 |
| 2F | Sp with only head PR | ↓ | 0.26 | 0.61624 | 4.29 | 0.04811 | 10.61 | 0.00001 |
| Vehicle group | Trained group | |||||||
| 2C | Shaft PR | ↓ | 3.98 | 0.05483 | 5.86 | 0.02133 | 5.59 | 0.00191 |
| 3B | Sp with no PR, PSD < 0.15 μm2 | ↑ | 0.74 | 0.39566 | 8.68 | 0.00597 | 2.79 | 0.04841 |
| 4D | Sp without SA, no PR | ↑ | 3.95 | 0.05586 | 14.01 | 0.00072 | 5.30 | 0.00266 |
| 5D | Sp without SA, no astro, head PR | ↓ | 1.43 | 0.24144 | 10.58 | 0.00270 | 5.32 | 0.00260 |
| 5E | Sp without SA, with astro, no PR | ↑ | 2.40 | 0.13117 | 22.53 | 0.00004 | 9.80 | 0.00002 |
Shown are measures of main effects of drug, an effect of drug in the box condition, or an effect of drug in the trained condition in the absence of a training effect. Nonsignificant effects are shown in italics. PR, Polyribosomes; Sp, spine; astro, perisynaptic astroglia.