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. 2017 Feb 15;37(7):1900–1909. doi: 10.1523/JNEUROSCI.3222-16.2017

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Copyright © 2017 Akle, Stankiewicz et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License Creative Commons Attribution 4.0 International, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 5. — Intrinsic and entrained circadian variation in mRNA abundance for p20 and core clock genes. Shown are circadian patterns of mRNA abundance for Clock1 (A), Per1 (B), and p20 (C) under LD (solid line) and DD (dashed line) conditions. n = 5–6 fish per time point; mean ± SEM. The gray background indicates night, 14:10 LD cycle. ZT of sample collection, ZT0 is lights-on time. Intrinsic circadian rhythm in DD, *p < 0.05, relative to the time of trough for mRNA abundance for each gene in DD (ZT23 for Clock1, ZT11 for Per1, ZT3′ for p20). Reduction in mRNA abundance at peak, DD versus LD, ^#p < 0.05 (ZT15 for Clock1 and p20, ZT23 for Per1).