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. 2017 Feb 15;37(7):1950–1964. doi: 10.1523/JNEUROSCI.3196-16.2017

Figure 6.

Figure 6.

Weaker E-S coupling in ventral CA1 pyramidal cells. A, Depolarization induced by somatic current injection elicits similar numbers of APs in dorsal and ventral pyramidal cells (n = 13 dorsal and n = 12 ventral cells, p = 0.694, two-way ANOVA: F(1,138) = 0.155). B, Traces represent examples of APs elicited by 50 and 100 pA current injections in dorsal and ventral cells. Calibration: 20 mV, 100 ms. C, The ability of EPSPs to elicit postsynaptic APs is significantly reduced in ventral pyramidal cells. *p < 0.01 (two-way ANOVA with Student-Newman-Keuls post hoc multiple-comparisons test). **p < 0.001 (two-way ANOVA with Student-Newman-Keuls post hoc multiple-comparisons test). p = 2.3 × 10−7, F(1,62) = 33.794 (n = 10 dorsal and n = 7 ventral cells). D, Traces represent examples of postsynaptic responses evoked by small (top, EPSP slope ≈ 5 mV/ms) and larger EPSPs (bottom, EPSP slope ≈ 8 mV/ms). Calibration: 10 mV, 20 ms.