Fig. 8.

Depth fraction and length of haplotype chains. Plot showing the lengths of haplotype chains against the depth fraction of the chains in a 100-kbp region near the GNAS locus for the WA9 sample. Each point is a chain and the size indicates the number of reads within it. To reduce noise and to extract the dominating haplotype chains, chains falling to the left of the straight line are removed as they either have a short length or contain a low fraction of the reads in the region. Green: removed chains. Brown: kept chains. The exact same cut-off was applied to all samples in all analyses. The chains are plotted against the genomic position in Fig. 9 and in Fig. 3 after the removal of noise