Table 2.

WGBS and NOMe-seq data sets

				Mapped	Read/
Sample name	Description	Method	Layout	reads	paired length	GEO	Ref
WA9	Human embryonic stem cell line	WGBS	Paired	1360M	100/186	GSM1521762	[25]
Colon normal A	Sigmoid colon tissue	WGBS	Single	1703M	101/ –	GSM983645	[26]
Colon normal B	Primary colon adjacent to tumor tissue	WGBS	Paired	789M	100/191	GSM1204466	[15]
Colon tumor B	Colon primary adenocarcinoma	WGBS	Paired	807M	100/191	GSM1204465	[15]
PrEC	Prostate epithelial cells	NOMe-seq	Paired	293M	73/128	GSE94361	–
LNCaP	Prostate adenocarcinoma cell line	NOMe-seq	Paired	329M	100/146	GSE94361	–

In the text, we refer to the data sets by their sample names. The data sets colon normal A, PrEC, and LNCaP have lower data quality than the other data sets. The read/paired length is approximate. See Additional file 1: Figure S28 for the position-wise read depth for all samples

WGBS whole-genome bisulfite sequencing