Table 2.
Patient characteristics associated with lack of conversion to functional AV access in patients starting hemodialysis with nonfunctional AV access or with catheter only
| Characteristics | Vascular access at baseline | P-value for interactiona | |||
|---|---|---|---|---|---|
| Nonfunctional AV access | Catheter only | ||||
| aOR (95% CI) | P-value | aOR (95% CI) | P-value | ||
| Women | 1.25 (1.10–1.43) | 0.0009 | 1.28 (1.20–1.36) | <0.0001 | 0.9514 |
| Age (1-year increase) | 1.01 (1.01–1.02) | <0.0001 | 1.02 (1.01–1.02) | <0.0001 | 0.0117 |
| Primary renal disease | 0.5615 | <0.0001 | 0.0938 | ||
| Hypertensive/Vascular | 0.94 (0.73–1.22) | 0.93 (0.83–1.04) | |||
| Diabetic nephropathy | 0.94 (0.71–1.25) | 0.84 (0.74–0.95) | |||
| Glomerulonephritis | |||||
| Polycystic kidney disease | 1.11 (0.76–1.61) | 0.79 (0.64–0.97) | |||
| Other | 1.13 (0.87–1.47) | 1.19 (1.07–1.33) | |||
| Unknown | 1.00 (0.75–1.34) | 1.15 (1.03–1.29) | |||
| Diabetes | 0.92 (0.77–1.10) | 0.3405 | 0.99 (0.92–1.07) | 0.8856 | 0.6441 |
| Number of cardiovascular comorbidities | 0.0008 | <0.0001 | 0.4444 | ||
| 0 | |||||
| 1 | 1.19 (1.01–1.40) | 1.12 (1.04–1.21) | |||
| 2 | 1.27 (1.04–1.54) | 1.39 (1.28–1.52) | |||
| 3 | 1.45 (1.16–1.82) | 1.58 (1.42–1.75) | |||
| 4 or 5 | 2.09 (1.55–2.82) | 1.88 (1.63–2.17) | |||
| Lower limb amputation | 1.13 (0.73–1.74) | 0.5884 | 1.26 (1.07–1.47) | 0.0050 | 0.3740 |
| Malignancy | 1.23 (0.99–1.52) | 0.0592 | 1.65 (1.51–1.79) | <0.0001 | 0.0056 |
| Mobility status | <0.0001 | <0.0001 | 0.0105 | ||
| Autonomous | |||||
| Needs assistance | 1.41 (1.17–1.69) | 1.61 (1.48–1.74) | |||
| Totally dependent | 2.05 (1.55–2.70) | 2.90 (2.56–3.28) | |||
| Body mass index (kg/m2) | 0.9333 | 0.0003 | 0.0856 | ||
| <18.5 | 1.03 (0.73–1.47) | 1.21 (1.07–1.36) | |||
| [18.5–25.0] | |||||
| [25.0–30.0] | 1.01 (0.86–1.19) | 0.96 (0.89–1.03) | |||
| ≥30.0 | 1.03 (0.86–1.23) | 0.85 (0.78–0.94) | |||
| Serum albumin (1-g/l increase) | 0.99 (0.98–1.01) | 0.3773 | 0.99 (0.99–1.00) | 0.0033 | 0.2750 |
| Anemia (hemoglobin <10 g/dl) | 0.95 (0.83–1.10) | 0.5156 | 0.91 (0.85–0.97) | 0.0027 | 0.6696 |
| Predialysis ESA treatment | 1.12 (0.98–1.27) | 0.0899 | 1.04 (0.97–1.11) | 0.3031 | 0.3383 |
| Estimated glomerular filtration rate (MDRD ml/min/1.73 m2) | 0.0037 | <0.0001 | 0.9829 | ||
| eGFR≤5 | 0.68 (0.54–0.86) | 0.75 (0.68–0.83) | |||
| 5<eGFR≤10 | 0.88 (0.74–1.03) | 0.91 (0.84–0.99) | |||
| 10<eGFR≤15 | |||||
| 15<eGFR≤20 | 1.11 (0.83–1.48) | 1.19 (1.04–1.37) | |||
| eGFR>20 | 1.38 (0.90–2.12) | 1.35 (1.13–1.60) | |||
| Facility type | 0.0001 | 0.0001 | 0.3805 | ||
| In center | |||||
| Satellite unit | 0.37 (0.19–0.73) | 0.59 (0.42–0.82) | |||
| Self-dialysis | 0.28 (0.14–0.57) | 0.48 (0.35–0.65) | |||
| Facility ownership | 0.0790 | 0.1452 | 0.6509 | ||
| Public university | |||||
| Public non-university | 0.77 (0.66–0.91) | 0.82 (0.76–0.89) | |||
| Private for-profit | 0.78 (0.66–0.92) | 0.79 (0.73–0.85) | |||
| Private not-for-profit | 1.11 (0.88–1.40) | 0.94 (0.85–1.05) | |||
a P-value for interaction between patient characteristic and AV access at baseline. ORs were adjusted for year of hemodialysis initiation and for all variables in Table 2. Abbreviations: aOR adjusted odds ratio, CI confidence interval, AV arteriovenous, ref reference, ESA erythropoiesis-stimulating agents, MDRD Modification of Diet in Renal Disease