Table 3.
Comparison of patients’ outcome between studied groups
| Variable | Total | Control group | hADSC-treated group | p |
|---|---|---|---|---|
| Wexner score (mean ± SD) | ||||
| Baseline | 8.17 ± 3.74 | 6.0 ± 1.18 | 10.33 ± 0.87 | 0.02* |
| Post intervention | 4.56 ± 3.22 | 2.67 ± 0.62 | 6.44 ± 1.08 | 0.36# |
| Standardized mean difference (95% confidence interval)a | 3.73 (2.61–4.86) | 3.63 (2.0–5.07) | 3.97 (2.31–5.62) | 0.41 |
| Percentage of muscle occupied area (mean ± SD) | 15.25 ± 7.34 | 11.65 ± 7.74 | 18.85 ± 5.06 | 0.02* |
| Electromyography recording (n, %) | ||||
| Negative | 10 (58.82) | 9 (100.0) | 1 (12.50) | 0.002* |
| Positive | 7 (41.18) | 0 (0.0) | 7 (87.50) | |
Control group sphincteroplasty alone, hADSC-treated group human adipose-derived stem cells + sphincteroplasty, SD standard deviation
aBased on Hedge’s g
*Based on Mann–Whitney U test
#Based on nonparametric ANCOVA test