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a Time from delivery of the intraperitoneal injection to loss of the righting reflex was longest in the low-dose low-volume group (LL). LH = low-dose high-volume group, HH = high-dose high-volume group. *p < 0.05 **p = 0.01. b Time from loss of the righting reflex to apnea was shortest in the high-dose high-volume group (HH). *p < 0.05 **p = 0.002 ***p < 0.001
