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Multiple gp130-responsive signaling pathways are activated in human and mouse colorectal cancer. (A) Paraffin-embedded sections of surgically removed human CRC (n = 17) and matched normal colon tissues (n = 7) were stained with P-Src, YAP, P-STAT3, or HES1 antibodies. (B) Paraffin-embedded colon sections from tumor-bearing CPC-APC mice (n = 3) and WT controls (n = 3) were stained as above. (Scale bars, 100 μm.)
