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YAP or STAT3 ablation inhibits intestinal tumorigenesis. (A) Representative images of Apc+/ΔIEC and Apc+/ΔIEC;Vil-gp130Act SIs. (Scale bars, 10 mm.) (B) β-Catenin staining of paraffin-embedded SI sections from Apc+/ΔIEC and Apc+/ΔIEC;Vil-gp130Act mice. (Scale bars, 100 μm.) (C) Tumor numbers in the jejunum and ileum of the indicated mouse strains (n = 5–8 per group). Results are means ± SEM; *P < 0.05.
