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. 2017 Jan 27;114(7):1643–1648. doi: 10.1073/pnas.1620290114

Fig. S3.

Fig. S3.

(A) RNA extracted from WT and Apc−/− SI organoids was analyzed by qRT-PCR for expression of the indicated mRNA species. Results are means ± SEM (n = 3). *P < 0.05. (B) Apc−/− SI organoids were incubated with neutralizing IL-6 antibody or control IgG for 3 d, after which expression and phosphorylation of the indicated proteins was examined by IB analysis. (C) RNA extracted from WT and Apc−/− enteroids was analyzed by qRT-PCR for expression of the indicated mRNA species. Results are means ± SEM (n = 3). *P < 0.05. (D) RNAs extracted from Villin-CreERT2 x ApcF/F enteroids treated with 4-OHT at 1 μM for the indicated times were analyzed by qRT-PCR for expression of the indicated mRNA species. Results are means ± SEM (n = 3).