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SAXS profile of CRY1 and CLOCK:BMAL1 bHLH PAS-AB. (A) Guinier analysis of both CLOCK:BMAL1 bHLH PAS-AB and CRY1 PHR show no aggregation indicated by the linear dependence of log(l(q)) vs. q2. SAXS calculated molecular weight for CRY1 PHR: 45 kDa, CLOCK:BMAL1 bHLH PAS-AB: 78 kDa. (B) Kratky plot of CLOCK:BMAL1 dimer and CRY PHR show mostly folded character and an elongated shape.
