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. 2015 Nov 23;33(36):4259–4267. doi: 10.1200/JCO.2015.61.9023

Table 1.

Patient Characteristics

Variable Name Overall (N = 7,287) RS Testing P
No (n = 5,678) Yes (n = 1,609)
Age at diagnosis, mean (SD), years 71.6 (11.6) 73.4 (11.2) 65.3 (10.8) < .001
Age category, years
 < 55 733 (10) 447 (7.9) 286 (18) < .001
 55-64 762 (10) 445 (7.8) 317 (20)
 65-74 2,526 (35) 1,831 (32) 695 (43)
 75-84 2,479 (34) 2,179 (38) 300 (19)
 ≥ 85 787 (11) 776 (14) 11 (0.7)
Race/ethnicity
 White, non-Hispanic 5,896 (81) 4,572 (81) 1,324 (82) .22
 Nonwhite or Hispanic 612 (8.4) 481 (8.5) 131 (8.1)
 Race/ethnicity missing 779 (11) 625 (11) 154 (9.6)
Payer
 Medicare 5,407 (74) 4,453 (78) 954 (59) < .001
 Independence 1,880 (26) 1,225 (22) 655 (41)
Cancer stage
 I 5,542 (76) 4,280 (75) 1,262 (78) < .001
 II 1,550 (21) 1,224 (22) 326 (20)
 III 87 (1.2) 83 (1.5) 4 (0.2)
 Missing 108 (1.5) 91 (1.6) 17 (1.1)
Tumor grade
 1 2,018 (28) 1,622 (29) 396 (25) < .001
 2 3,190 (44) 2,331 (41) 859 (53)
 3 1,628 (22) 1,350 (24) 278 (17)
 4 41 (0.6) 39 (0.7) 2 (0.1)
 Missing 410 (5.6) 336 (5.9) 74 (4.6)
Tumor size, cm
 < 1 2,261 (31) 1,904 (34) 357 (22) < .001
 1-2 3,919 (54) 2,813 (50) 1,106 (69)
 > 2 797 (11) 680 (12) 117 (7.3)
 Missing 310 (4.3) 281 (4.9) 29 (1.8)
Diagnosis year
 2007 1,876 (26) 1,573 (28) 303 (19) < .001
 2008 1,831 (25) 1,421 (25) 410 (25)
 2009 1,819 (25) 1,408 (25) 411 (26)
 2010 1,761 (24) 1,276 (22) 485 (30)
Prior year health care spending, $
 Mean (SD) 6,028 (12,400) 6,261 (12,993) 5,205 (9,993) .003
 Median (IQR) 2,244 (4632) 2,288 (4,784) 2,144 (4,192) .25
Elixhauser22 comorbidity count
 0 1,388 (19) 989 (17) 399 (25) < .001
 1-3 4,087 (56) 3,157 (56) 930 (58)
 ≥ 4 1,812 (25) 1,532 (27) 280 (17)

NOTE. Data are presented as No. (% of the column’s total patients) unless otherwise specified.

Abbreviations: RS, 21-gene recurrence score assay; IQR, interquartile range.