TABLE 1.
Characteristics of discovery and replicate samples in GOLDN
| Discovery Sample (n = 653) | Replication Sample (n = 326) | |||||
| Men | Women | Both | Men | Women | Both | |
| n | 313 | 340 | 653 | 156 | 170 | 326 |
| Age, years | 48.1 (15.9) | 47.9 (16.4) | 48.0 (16.2) | 50.2 (17.3) | 47.6 (16.4) | 48.8 (16.9) |
| BMI, kg/m2 | 28.3 (4.6) | 28.2 (6.4) | 28.2 (5.6) | 28.5 (5.0) | 28.2 (6.4) | 28.3 (5.8) |
| Waist, inches | 100.0 (13.8) | 93.2 (17.8) | 96.5 (16.4) | 100.6 (13.6) | 93.1 (16.9) | 96.7 (15.8) |
| TG at baseline, mg/dl | 149.1 (111.0)a | 125.7 (82.2) | 136.9 (97.7) | 144.4 (90.1) | 127.2 (87.3) | 135.4 (89.0) |
| TG uptake slope | 0.18 (0.03) | 0.17 (0.03) | 0.18 (0.03) | 0.18 (0.03) | 0.18 (0.03) | 0.18 (0.03) |
| TG clearance slope | −0.06 (0.05) | −0.07 (0.05) | −0.07 (0.05) | −0.05 (0.05) | −0.07 (0.05) | −0.06 (0.05) |
| TG AUC | 31.6 (3.4)b | 30.4 (3.3) | 30.9 (3.4) | 31.6 (3.3)a | 30.3 (3.3) | 30.9 (3.4) |
| TG AUI | 2.5 (0.5) | 2.4 (0.5) | 2.4 (0.6) | 2.6 (0.6) | 2.4 (0.5) | 2.5 (0.6) |
Values are means (standard deviations).
a
P value for differences between men and women (within sample) significant with P < 0.05.
b
P value for differences between men and women (within sample) significant with P < 0.001.