TABLE 5.
Lipid-SNPs associate with DNA methylation in adipose tissue
| CpG ID | rs13228738 | rs3211842 | rs1722507 | rs1761665 | rs7755 |
| cg18508525a | 9.65 × 10−06 | 3.83 × 10−04 | 2.76 × 10−07 | 3.20 × 10−05 | 3.04 × 10−04 |
| cg25783969a | 1.24 × 10−08 | — | 7.23 × 10−11 | 6.72 × 10−05 | 9.26 × 10−05 |
| cg21055948a | 1.57 × 10−11 | 5.01 × 10−06 | 2.37 × 10−13 | 3.08 × 10−07 | 6.14 × 10−06 |
| cg19096849 | 3.36 × 10−09 | 5.87 × 10−06 | 3.64 × 10−11 | 1.40 × 10−07 | 7.97 × 10−07 |
| cg26138637a | — | — | 8.38 × 10−05 | — | — |
| cg06601993 | — | — | 6.75 × 10−04 | 4.00 × 10−04 | — |
Adipose tissue CpG methylation levels determined in the MuTHER study using the Infinium HumanMethylation450 platform. CpGs listed based on chromosomal position. p-values are for CpG-SNP associations.
a
CpG associates with adipose CD36 mRNA (Table 6).