Table 1. Baseline characteristics of the study population.
| Bilirubin ≥ 0.8 (n = 629) | Bilirubin < 0.8 (n = 499) | P | |
|---|---|---|---|
| Age (years) | 61 (54–71) | 66 (58–73) | < 0.001 |
| Sex (male) | 323 (53.1) | 189 (40.0) | < 0.001 |
| Body mass index (kg/m2) | 24.8 (22.4–27.9) | 24.4 (21.8–27.4) | 0.18 |
| Total bilirubin (mg/dL) | 0.9 (0.8–1.1) | 0.6 (0.5–0.7) | < 0.001 |
| Serum creatinine (mg/dL) | 0.90 (0.70–1.00) | 0.80 (0.70–1.00) | 0.10 |
| eGFR (mL/min/1.73 m2) | 84.5 (74.0–94.0) | 82.0.3 (70.0–95.1) | 0.10 |
| Calcium (mg/dL) | 9.0 (8.8–9.3) | 8.9 (8.6–9.2) | < 0.001 |
| Albumin (g/L) | 4.2 (4.0–4.3) | 4.1 (3.9–4.3) | < 0.001 |
| AST (IU/L) | 23 (20–29) | 22 (18–27) | 0.001 |
| ALT (IU/L) | 20 (15–28) | 18 (14–26) | 0.001 |
| ALP (IU/L) | 75 (63–91) | 75 (63–93) | 0.90 |
| Total Cholesterol (mg/dL) | 180 (149–206) | 174 (139–202) | 0.02 |
| HDL (mg/dL) | 44 (36–53) | 43 (34–51) | 0.08 |
| LDL (mg/dL) | 92 (52–133) | 93 (57–131) | 0.86 |
| Tg (mg/dL) | 96 (62–148) | 97 (64–153) | 0.47 |
| Hypertension | 516 (84.9) | 433 (91.7) | 0.001 |
| Diabetes mellitus | 51 (8.4) | 74 (15.7) | < 0.001 |
| Stroke | 99 (1.5) | 7 (1.5) | > 0.99 |
| Coronary artery disease | 33 (5.4) | 26 (5.5) | > 0.99 |
| Cancer | 14 (2.3) | 27 (5.7) | 0.006 |
| ACE I/ARBs | 125 (20.6) | 126 (26.7) | 0.02 |
| Diuretics | 57 (9.4) | 66 (14.0) | 0.023 |
| Statins | 134 (22.0) | 136 (28.8) | 0.013 |
eGFR, estimated glomerular filtration rate, AST, aspartate aminotransferase, ALT, alanine aminotransferase, ALP, alkaline phosphatase, HDL, high density lipoprotein, LDL, low density lipoprotein, ACE I, angiotensin converting enzyme inhibitor, ARB, angiotensin receptor blocker