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. 2017 Feb 9;11(2):e0005378. doi: 10.1371/journal.pntd.0005378

Table 1. State variables, parameters definitions and values used in the model.

Where two numbers are listed for ψ, they indicate the values used for TF 40% and 20% communities.

Name Definition Value Units Source
Si Susceptible individuals Number
Ii Infected but not infectious Number
IDi Infected and Infectious (PCR and TF +ve) Number
Di Diseased and not infectious (TF +ve) Number
PDi Partially diseased can be re-infected (TF +ve) Number
IOi Infected and infectious (PCR +ve) Number
β Transmission rate parameter Estimated Proportion
ϵ Degree of random mixing in the population 0.5 Proportion [11]
c Coverage level of treatment 80% Percentage
e Efficacy of treatment 85% Percentage [12, 31]
Ninfs Maximum number of infections before immunity saturates 100 Number [11]
N Total number of individuals in the population 6000 Number
α Infectivity of an individual proportional to the log of their bacterial load 0–1 Proportion [11]
ρ1 Minimum rate of recovery from active disease after 1st infection Estimated Day−1 [8, 11]
ρ100 Maximum rate of recovery from active disease after 100th infection 1/7 Day−1 [8, 11]
ω1 Minimum rate of recovery from 1st infection Estimated Day−1 [8, 11]
ω100 Maximum rate of recovery from 100th infection 1/77 Day−1 [8, 11]
θ Rate of change of the recovery from disease rate per infection 0.30 Proportion [8, 11]
ϕ Rate of change of the recovery from infection rate per infection 0.45 Proportion [8]
π Rate of change of infectivity rate per infection Estimated Proportion [8, 11]
ψ Non-linear power term 1.2, 1.4 Number [9]
ζ1 Rate of recovery from PD with 1st infection 1/134 Day−1 [8, 18]
ζ100 Rate of recovery from PD with 100th infection 1/7 Day−1 [8, 18]
η1 Rate of recovery from IO with 1st infection 1/77 Day−1 [8]
η100 Rate of recovery from IO with 100th infection 1/38 Day−1 [8]
σ Rate at which infected individuals become infectious 1/14 Day−1 [8]
λa Age-specific force of infection Calculated
v2 Non-linear constant term 2.6 Number [9]
Γ Susceptibility to re-infection in the disease state 0, 0.20, 0.50, 0.80 Proportion [18]