Table 3. SNP-SNP interaction models identified by the GMDR method with adjustment for age, gender, and education.
Best interaction model | Testing accuracy (%) | P value |
---|---|---|
ADAMTS9 rs9985304, ADAMTS9 rs76346246 | 68.72 | < 0.001 |
ADAMTS9 rs4317088, ADAMTS9 rs4566532, ADAMTS9 rs7642530 | 67.40 | < 0.001 |
GMDR = generalized multifactor dimensionality reduction.
P value was based on 1,000 permutations. Analysis was obtained after adjustment for covariates including age, gender, and education. P values of < 0.05 are shown in bold.