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. 2017 Feb 22;12(2):e0172440. doi: 10.1371/journal.pone.0172440

Table 3. SNP-SNP interaction models identified by the GMDR method with adjustment for age, gender, and education.

Best interaction model Testing accuracy (%) P value
ADAMTS9 rs9985304, ADAMTS9 rs76346246 68.72 < 0.001
ADAMTS9 rs4317088, ADAMTS9 rs4566532, ADAMTS9 rs7642530 67.40 < 0.001

GMDR = generalized multifactor dimensionality reduction.

P value was based on 1,000 permutations. Analysis was obtained after adjustment for covariates including age, gender, and education. P values of < 0.05 are shown in bold.