Table 2.

Pooled analysis of the effect of any aspirin versus control in secondary prevention after TIA and ischaemic stroke on the early risk of any recurrent ischaemic stroke and on disabling or fatal ischaemic stroke stratified by the nature of the presenting event (TIA and minor stroke vs major stroke) and by time from presenting event to randomisation (≤14 days vs >14 days)

		0–6 weeks			6–12 weeks			0–12 weeks			pinteraction
		Events	HR (95% CI)	p	Events	HR (95% CI)	p	Events	HR (95% CI)	p
Presenting event
Any ischaemic stroke
	TIA or minor stroke	169	0·38 (0·27–0·53)	<0·0001	92	0·63 (0·41–0·95)	0·028	261	0·46 (0·35–0·59)	<0·0001	0·75
	Major stroke	90	0·50 (0·32–0·77)	0·0018	28	0·51 (0·23–1·10)	0·088	118	0·50 (0·34–0·73)	0·0004	..
Disabling or fatal ischaemic stroke
	TIA or minor stroke	74	0·19 (0·11–0·34)	<0·0001	41	0·43 (0·22–0·82)	0·010	115	0·26 (0·17–0·40)	<0·0001	0·15
	Major stroke	72	0·42 (0·25–0·69)	0·0007	23	0·59 (0·25–1·36)	0·21	95	0·46 (0·30–0·70)	0·0004	..
Time since last event
Any ischaemic stroke
	Time since last event ≤14 days	80	0·54 (0·34–0·85)	0·0082	34	0·66 (0·33–1·31)	0·24	114	0·57 (0·39–0·84)	0·0042	0·15
	Time since last event >14 days	131	0·34 (0·23–0·50)	<0·0001	72	0·56 (0·34–0·90)	0·016	203	0·41 (0·30–0·55)	<0·0001	..
Disabling or fatal ischaemic stroke
	Time since last event ≤14 days	43	0·41 (0·21–0·78)	0·0071	21	0·58 (0·24–1·40)	0·22	64	0·46 (0·27–0·77)	0·0035	0·13
	Time since last event >14 days	77	0·21 (0·12–0·38)	<0·0001	36	0·45 (0·22–0·90)	0·025	113	0·28 (0·18–0·43)	<0·0001	..

Data for time since last event were only available in 12 839 patients.