Table 1. High PIP4K2B expression correlates with ERBB2 expression and low PIP4K2B expression associates with worse clinical parameter.

Correlation between PIP4K2B staining and clinico-pathological and molecular parameters of advanced breast cancer. Significant P values are marked in bold.

	PIP4K2B					P-Chi-Sq
Variable and categories		1	2	3	Total	P
Her 2	0	188	151	58	397	0.000
	2+	10	13	11	34
	3+	15	18	16	49
Median age (range)		65(28-92)	65(27-96)	63(34-90)
		221	183	85	489	0.165
Nhg	1	43	57	22	122	0.007
	2	91	68	44	203
	3	87	57	19	163
Size (median)		19	15	15
		221	183	85	489	0.021
Lymph node status	0	117	109	49	275	0.375
	1	79	59	23	161
ki67	0-10	65	76	34	175	0.011
	11-25	67	60	28	155
	>25	74	38	16	128
ER	0	37	19	13	69	0.174
	1	181	161	71	422
PR	0	53	30	17	102	0.332
	1	162	146	67	375
Tumour type	Ductal	139	122	63	324
	Lobular	33	26	11	70
Distant metastasis	no	113	115	53	281	0.040
during follow-up	yes	52	23	13	88
	unknown	54	43	19	116