TABLE.
Adverse Events for Fornix-Based Versus Limbal-Based Trabeculectomy
| Adverse Event | Number of Trials | Number of Participants | Odds Ratio [95% Confidence Interval] |
|---|---|---|---|
| Complications | |||
| Wound leak | 3 | 185 | 1.20 [0.37 to 3.87] |
| Hypotony | 3 | 198 | 1.97 [0.68 to 5.74] |
| Shallow anterior chamber | 4 | 302 | 0.44 [0.22 to 0.92] |
| Bleb infection | 1 | 86 | 0.33 [0.01 to 8.22] |
| Choroidal detachment | 2 | 125 | 0.60 [0.13 to 2.85] |
| Choroidal effusion | 2 | 146 | 0.55 [0.15 to 1.97] |
| Hyphema | 3 | 215 | 0.66 [0.20 to 2.17] |
| Corneal toxicity | 2 | 112 | 1.39 [0.45 to 4.30] |
| Conjunctival bleb leak within 3 months | 1 | 86 | 15.08 [0.82 to 276.66] |
| Conjunctival bleb leak after 3 months | 1 | 86 | 0.19 [0.01 to 4.09] |
| Avascularized bleb | 1 | 62 | 2.74 [0.88 to 8.55] |
| Hypertrophy of bleb | 1 | 100 | 0.13 [0.01 to 2.60] |
| Iridocyclitis | 1 | 100 | 0.64 [0.17 to 2.41] |
| Intraoperative trauma to lens | 1 | 100 | 0.65 [0.10 to 4.09] |
| Cataract requiring surgery | 1 | 100 | 0.14 [0.03 to 0.71] |
| Capsule opacification | 1 | 60 | 1.00 [0.28 to 3.54] |
| Cystic bleb/bleb fibrosis | 1 | 60 | 1.56 [0.24 to 10.05] |
| Fibrin exudation | 1 | 60 | 0.69 [0.21 to 2.30] |
| Pupillary membrane | 1 | 60 | 0.46 [0.08 to 2.75] |
| Cystoid macular edema | 1 | 69 | 2.38 [0.09 to 60.42] |
| Hemiretinal vein occlusion | 1 | 69 | 0.25 [0.01 to 6.33] |
| Postoperative procedures | |||
| Needling with 5-fluorouracil | 2 | 155 | 0.63 [0.22, 1.81] |
| Suture lysis procedure | 3 | 211 | 1.07 [0.50, 2.29] |
| Digital massage | 1 | 86 | 1.63 [0.53 to 5.07] |
| Releasable suture removal | 1 | 60 | 0.85 [0.27 to 2.67] |
| Repair of wound | 1 | 69 | 0.49 [0.08 to 3.11] |