Table 1.
Baseline characteristics of patients with and without obstructive CAD in the TRIUMPH and PREMIER registries
| No obstructive CAD (n = 381) | Obstructive CAD (n = 4941) | P-value | |
|---|---|---|---|
| Mean age (years) | 56.7 ± 12.6 | 59.8 ± 12.1 | <0.001 |
| Female sex | 57.0% | 30.0% | <0.001 |
| Non-white race | 51.1% | 23.6% | <0.001 |
| Married | 46.5% | 59.7% | <0.001 |
| Low social support | 19.7% | 15.1% | 0.017 |
| High school education | 76.9% | 80.9% | 0.057 |
| Hypertension | 68.8% | 63.4% | 0.037 |
| Mean total cholesterol | 178.3 ± 51.0 | 173.2 ± 40.0 | 0.074 |
| Mean triglycerides | 157.8 ± 167.4 | 125.7 ± 105.4 | <0.001 |
| Mean HDL cholesterol | 41.9 ± 13.6 | 50.5 ± 18.5 | <0.001 |
| Mean LDL cholesterol | 106.1 ± 41.3 | 98.9 ± 34.4 | 0.002 |
| Prior MI | 16.8% | 20.2% | 0.107 |
| Current smoker | 33.7% | 37.3% | 0.159 |
| Diabetes mellitus | 20.7% | 28.5% | 0.001 |
| PHQ depression score | 6.2 ± 5.8 | 5.2 ± 5.4 | <0.001 |
| ST-elevation MI | 13.4% | 49.0% | <0.001 |
| Mean GRACE mortality score at discharge | 106.7 ± 28.6 | 100.1 ± 29.4 | <0.001 |
| Troponin peak (ng/dL; median [IQR]) | 2.4 (0.6, 8.0) | 7.6 (1.9, 37.7) | <0.001 |
| In-hospital PCI | 0.0% | 76.7% | <0.001 |
| In hospital CABG | 0.0% | 12.1% | <0.001 |
| Discharge management | |||
| Cardiac rehabilitation referral | 21.3% | 48.2% | <0.001 |
| Aspirin prescription | 85.6% | 95.1% | <0.001 |
| Clopidogrel prescription | 28.1% | 79.9% | <0.001 |
| Beta-blocker prescription | 76.6% | 91.7% | <0.001 |
| Statin prescription | 70.3% | 88.3% | <0.001 |
| ACE-I or ARB | 69.6% | 75.1% | 0.017 |
| Eplerenone or spironolactone | 6.3% | 3.9% | 0.025 |
CAD, coronary artery disease; MI, myocardial infarction; PHQ, Patient Health Questionnaire; GRACE: Global Registry of Acute Coronary Events; PCI, percutaneous coronary intervention; CABG: coronary artery bypass grafting; ACE-I, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker.