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. Author manuscript; available in PMC: 2017 May 13.

Published in final edited form as: ACS Infect Dis. 2016 Mar 29;2(5):341–351. doi: 10.1021/acsinfecdis.6b00031

SPR sensograms for the binding of mAb clone 45 to novel polymyxin lipopeptides (Black 0.0 µM, Blue 0.037 µM, Red 0.11 µM, Green 0.33 µM, Orange 1.0 µM, Dark Blue 3.0 µM). The insets show the chemical structure of each lipopeptide and the modified regions that differ from the polymyxin B core scaffold are colored red.

SPR sensograms for the binding of mAb clone 45 to novel polymyxin lipopeptides (Black 0.0 µM, Blue 0.037 µM, Red 0.11 µM, Green 0.33 µM, Orange 1.0 µM, Dark Blue 3.0 µM). The insets show the chemical structure of each lipopeptide and the modified regions that differ from the polymyxin B core scaffold are colored red.