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. Author manuscript; available in PMC: 2017 May 13.
Published in final edited form as: ACS Infect Dis. 2016 Mar 29;2(5):341–351. doi: 10.1021/acsinfecdis.6b00031

Figure 4.

Figure 4

Monoclonal antibiody clone 45 epitope ‘HOTSPOTS’ on the polymyxin B structure. The SPR KD values were mapped onto the NMR solution structure of polymyxin B1 (higher affinity binding is represented by a brighter red coloring). The polymyxin B1 structure is shown in CPK representation and the two views are rotated by 180° about the y-axis.