Table 3.

Regional distribution volume (V_T) estimates from the three different methods for each of the groups. Data are expressed as mean ± SD for the tracer dose group (n = 10) and as individual values for the pre-saturated group (n = 2)

		VT
Region	2TCM	1TCM	SA
Tracer dose (n = 10)
Frontal cortex	7.81 ± 1.10	7.80 ± 2.38	7.15 ± 1.17
Hippocampus	6.86 ± 0.94	6.84 ± 2.08	6.55 ± 0.95
Cerebellum*	4.44 ± 0.67	4.11 ± 1.24	4.33 ± 0.65
Medulla*	2.77 ± 0.48	2.35 ± 0.71	2.66 ± 0.39
Pons*	2.54 ± 0.40	2.10 ± 0.61	2.45 ± 0.33
Pre-saturated (n = 2)
Frontal cortex	1.23 and 1.10	0.67 and 0.73	1.00 and 0.89
Hippocampus	1.07 and 0.92	0.60 and 0.62	1.09 and 0.68
Cerebellum	0.98 and 0.91	0.52 and 0.58	1.00 and 0.69
Medulla	0.89 and 0.80	0.46 and 0.56	0.69 and 0.83
Pons	0.99 and 0.88	0.55 and 0.59	0.80 and 0.72

*Significant differences were found in these regions between 1TCM and 2TCM estimates (p < 0.005) as well as between 1TCM and SA (p < 0.05)