Table 6.
Adverse events occurring in more than 20 % of patients according to surgical procedure
| Adverse event, n (%) | Total gastrectomy (n = 36) | Distal gastrectomy (n = 64) | ||
|---|---|---|---|---|
| All grades | Grade 3/4 | All grades | Grade 3/4 | |
| Peripheral sensory neuropathy | 33 (92) | 6 (17) | 61 (95) | 8 (13) |
| Nausea | 35 (97) | 6 (17) | 52 (81) | 4 (6) |
| Neutropenia | 24 (67) | 12 (33) | 52 (81) | 21 (33) |
| Diarrhea | 25 (69) | 1 (3) | 42 (66) | 1 (2) |
| Decreased appetite | 25 (69) | 6 (17) | 41 (64) | 11 (17) |
| Hand–foot syndrome | 16 (44) | 0 | 32 (50) | 0 |
| Vomiting | 15 (42) | 3 (8) | 31 (48) | 2 (3) |
| Infusion site pain | 15 (42) | 0 | 30 (47) | 1 (2) |
| Fatigue | 17 (47) | 3 (8) | 26 (41) | 3 (5) |
| Thrombocytopenia | 10 (28) | 1 (3) | 33 (52) | 5 (8) |
| Leukopenia | 10 (28) | 1 (3) | 22 (34) | 0 |
| Dysgeusia | 9 (25) | 0 | 19 (30) | 0 |
| Malaise | 7 (19) | 1 (3) | 21 (33) | 1 (2) |
| Stomatitis | 9 (25) | 0 | 17 (27) | 0 |
| Constipation | 9 (25) | 0 | 16 (25) | 0 |
| Weight decreased | 9 (25) | 1 (3) | 11 (17) | 0 |
| Hepatic function abnormal | 5 (14) | 0 | 16 (25) | 0 |