Table 1.
Univariate analysis of overall survival (OS) for all patients
| Gene symbol | Log-rank P | BH-FDR_P | Hazard ratio | 95 % low | 95 % high |
|---|---|---|---|---|---|
| IGF1R | 8.64E−05 | 0.005 | 1.64 | 1.28 | 2.10 |
| AREG | 3.70E−04 | 0.020 | 0.64 | 0.50 | 0.82 |
| ERBB2 | 2.04E−03 | 0.110 | 1.47 | 1.15 | 1.88 |
| GZMA | 7.23E−03 | 0.383 | 0.70 | 0.54 | 0.91 |
| LRP5 | 8.06E−03 | 0.419 | 1.40 | 1.09 | 1.79 |
| THBS1 | 1.90E−02 | 0.968 | 1.34 | 1.05 | 1.71 |
| EZH2 | 4.93E−02 | 0.979 | 0.78 | 0.60 | 1.00 |
| DAPK1 | 5.37E−02 | 0.979 | 1.28 | 1.00 | 1.65 |
| UPP1 | 5.78E−02 | 0.979 | 0.79 | 0.62 | 1.01 |
| CAV1 | 5.80E−02 | 0.979 | 1.27 | 0.99 | 1.62 |
| ANGPT2 | 6.17E−02 | 0.979 | 1.27 | 0.99 | 1.64 |
| DHFR | 7.83E−02 | 0.979 | 0.80 | 0.63 | 1.03 |
| TYMP | 8.34E−02 | 0.979 | 0.80 | 0.63 | 1.03 |
| DUT | 9.70E−02 | 0.979 | 0.81 | 0.64 | 1.04 |
| EREG | 9.70E−02 | 0.979 | 0.78 | 0.58 | 1.05 |
| SPARC | 1.25E−01 | 0.979 | 1.21 | 0.95 | 1.54 |
| MAPT | 1.33E−01 | 0.979 | 1.24 | 0.94 | 1.65 |
| EGFR | 1.42E−01 | 0.979 | 1.20 | 0.94 | 1.54 |
| FAS | 1.42E−01 | 0.979 | 0.83 | 0.64 | 1.07 |
| PTGS2 | 1.58E−01 | 0.979 | 0.83 | 0.65 | 1.07 |
| PECAM1 | 2.11E−01 | 0.979 | 1.17 | 0.92 | 1.49 |
| RRM1 | 2.21E−01 | 0.979 | 1.17 | 0.91 | 1.49 |
| TGFA | 2.28E−01 | 0.979 | 1.17 | 0.91 | 1.51 |
| GADD45A | 2.36E−01 | 0.979 | 1.18 | 0.89 | 1.57 |
| MUC2 | 2.39E−01 | 0.979 | 0.85 | 0.65 | 1.11 |
| HPSE | 2.71E−01 | 0.979 | 0.87 | 0.68 | 1.11 |
| TYMS | 2.91E−01 | 0.979 | 0.88 | 0.69 | 1.12 |
| RUNX3 | 3.25E−01 | 0.979 | 0.88 | 0.69 | 1.13 |
| LDHA | 3.33E−01 | 0.979 | 0.89 | 0.69 | 1.13 |
| PTEN | 3.36E−01 | 0.979 | 0.89 | 0.69 | 1.13 |
| PLA2G2A | 3.70E−01 | 0.979 | 0.87 | 0.65 | 1.17 |
| REG4 | 3.80E−01 | 0.979 | 0.89 | 0.70 | 1.15 |
| ABCC1 | 4.00E−01 | 0.979 | 1.11 | 0.87 | 1.42 |
| TOP1 | 4.07E−01 | 0.979 | 0.90 | 0.71 | 1.15 |
| ABCB1 | 4.66E−01 | 0.979 | 0.91 | 0.70 | 1.18 |
| E2F1 | 4.70E−01 | 0.979 | 0.91 | 0.71 | 1.17 |
| GGH | 5.91E−01 | 0.979 | 1.07 | 0.83 | 1.38 |
| FPGS | 6.15E−01 | 0.979 | 1.07 | 0.83 | 1.36 |
| TOP2A | 6.55E−01 | 0.979 | 1.06 | 0.83 | 1.35 |
| ITGB3 | 6.70E−01 | 0.979 | 1.05 | 0.83 | 1.35 |
| BCL2L11 | 6.75E−01 | 0.979 | 0.93 | 0.68 | 1.28 |
| APC | 6.95E−01 | 0.979 | 0.95 | 0.75 | 1.22 |
| ERCC1 | 7.29E−01 | 0.979 | 1.04 | 0.82 | 1.33 |
| BCL2 | 7.30E−01 | 0.979 | 1.05 | 0.80 | 1.38 |
| VCAM1 | 7.40E−01 | 0.979 | 1.04 | 0.82 | 1.33 |
| RRM2 | 7.71E−01 | 0.979 | 0.96 | 0.75 | 1.23 |
| MGMT | 7.79E−01 | 0.979 | 0.97 | 0.75 | 1.24 |
| BAX | 8.23E−01 | 0.979 | 0.97 | 0.76 | 1.24 |
| VEGFA | 8.34E−01 | 0.979 | 1.03 | 0.80 | 1.31 |
| DPYD | 8.47E−01 | 0.979 | 1.02 | 0.80 | 1.31 |
| UMPS | 8.55E−01 | 0.979 | 0.98 | 0.76 | 1.26 |
| ESR1 | 9.12E−01 | 0.979 | 1.01 | 0.79 | 1.31 |
| MTHFR | 9.43E−01 | 0.979 | 1.01 | 0.78 | 1.31 |
| HDAC1 | 9.68E−01 | 0.979 | 1.00 | 0.79 | 1.28 |
| PLAU | 9.70E−01 | 0.979 | 1.00 | 0.79 | 1.28 |
| MLH1 | 9.79E−01 | 0.979 | 1.00 | 0.78 | 1.30 |
BH-FDR Benjamini & Hochberg false discovery rate