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. 2017 Feb;18(1):75–92. doi: 10.2174/1389202917666160808125213

Fig. (3).

Fig. (3)

Chemical structures of clinically important TOP1 inhibitors. Camptothecin (CPT) derivatives topotecan and irinotecan are clinically approved anticancer agents while indimitecan, indotecan and Genz-644282 are under clinical development. The structures were adopted from PubChem database. Respective PubChem CIDs are provided within the parentheses.