Fig. (5).

The cancer hallmarks modulated by Ranunculaceae phytometabolites. Ranunculaceae phytometabolites regulate all hallmarks of cancer, as defined by Hanahan and Weinberg [134]. The putative PARP inhibitor has not been identified from Ranunculaceae plants. Instead, various antioxidants found in Ranunculaceae might play important roles in fighting against genome instability and mutation of cancer cells.