Table 2.
Group | Genotype | Jmax estimate (pmol/min/mg lysate protein) |
---|---|---|
Wild | *1 × *1 | 29.0 |
Heterozygotes | *1 × *2 | 18.1 |
*1 × *3 | 17.6 | |
Homozygotes | *2 × *2 | 7.21 |
*2 × *3 | 6.73 |
Jmax was estimated as described in the Method section, based on the reported OCT1 variant‐dependent kinetic parameters.6
Jmax, maximal flux value; OCT1, organic cation transporter‐1.