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Jmax estimates for each OCT1 transporter genotype
| Group | Genotype | Jmax estimate (pmol/min/mg lysate protein) |
|---|---|---|
| Wild | *1 × *1 | 29.0 |
| Heterozygotes | *1 × *2 | 18.1 |
| *1 × *3 | 17.6 | |
| Homozygotes | *2 × *2 | 7.21 |
| *2 × *3 | 6.73 |
Jmax was estimated as described in the Method section, based on the reported OCT1 variant‐dependent kinetic parameters.6
Jmax, maximal flux value; OCT1, organic cation transporter‐1.
