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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: J Immunol. 2017 Jan 18;198(5):2165–2171. doi: 10.4049/jimmunol.1600801

Figure 4.

Figure 4

Etv5 enhances the binding of IL-10-inducing transcription factors. A, Expression of IL-10-inducing transcription factors in control and Etv5fl/fl CD4 Cre+ Th2 cells were measured using qRT-PCR. Th2 cells were restimulated with anti-CD3 for 6 hours followed by cDNA synthesis. B-C, ChIP analysis of IL-10 inducing transcription factors (B), or histone modifications and p300 (C) at the Il10 locus in WT or Etv5-deficient Th2 cells. Data are mean ± SEM of 2 independent experiments (n=4/experiment). *p < 0.05, **p <0.005