Table 2.

Components of the five Factors used in the general linear model regressions versus cortical thickness in the study.

Factor	1	2	3	4	5
Interpretation	Insulin/Metabolic	Glucose	Kidney function	Cholesterol	Protein
% variance explained	20.78	18.42	18.03	13.78	8.41
Insulin	0.82	0.19	−0.01	−0.08	0.06
HDL	−0.81	0.01	0.00	0.19	0.02
Chol/HDL ratio	0.81	−0.04	0.02	0.45	0.00
HOMA-IR	0.75	0.47	0.03	−0.10	0.03
Triglycerides	0.69	0.04	0.16	0.28	−0.01
Average Glucose	0.07	0.93	0.17	−0.13	−0.07
HbA1C	0.07	0.93	0.17	−0.13	−0.07
Fasting Glucose	0.17	0.86	0.10	−0.07	−0.10
eGFR	−0.03	−0.14	−0.92	0.02	−0.02
Creatinine	0.23	0.12	0.86	−0.11	0.11
BUN	0.15	0.27	0.77	−0.03	0.01
CCL	0.40	0.06	−0.76	−0.12	0.13
Cholesterol	−0.08	−0.13	−0.01	0.97	0.08
LDL	0.13	−0.17	−0.06	0.92	0.09
Total Protein	0.10	0.01	0.11	0.02	0.84
Albumin	−0.07	−0.20	−0.08	0.12	0.76

Bolded values indicate an absolute loading value of 0.40 or above. HDL = high density lipoprotein; LDL = low density lipoprotein; Chol =cholesterol; HbA1C = glycated hemoglobin; HOMA-IR = homeostatic model assessment of insulin resistance; BUN = blood urea nitrogen; eGFR = estimated glomerulus filtration rate; CCL = creatinine clearance