Table 3.

Association between maternal plasma selenium level and the child's risk of wheezing (n = 861)

	Maternal plasma selenium level (µg/L), OR [95%CI]*
	Unadjusted				Adjusted†
Outcome	High vs. low	p §	For a 10 µg/L increment	p	High vs. low	p	For a 10 µg/L increment	p
Asthma
By 1 year	0.93 [0.46–1.88]	0.46	0.99 [0.98–1.01]	0.50	0.99 [0.51–2.31]	0.89	1.00 [0.98–1.01]	0.77
By 3 years	0.73 [0.41–1.31]	0.31	0.97 [0.90–1.02]	0.07	0.83 [0.44–1.54]	0.67	0.99 [0.98–1.01]	0.30
Wheezing
By 1 year	0.75 [0.49–0.94]	0.02	0.94 [0.90–0.99]	0.04	0.74 [0.47–0.92]	0.03	0.96 [0.92–1.01]	0.06
By 3 years	0.87 [0.61–0.99]	0.04	0.97 [0.90–1.02]	0.07	0.89 [0.61–1.00]	0.05	0.98 [0.93–1.04]	0.10
Atopic dermatitis
By 1 year	1.33 [0.91–1.95]	0.18	1.00 [0.99–1.01]	0.25	1.44 [0.86–2.16]	0.62	1.00 [0.99–1.01]	0.24
By 3 years	0.98 [0.68–1.40]	0.04	1.00 [0.99–1.01]	0.78	1.17 [0.80–1.72]	0.30	1.00 [0.99–1.02]	0.73
Allergic rhinitis
By 1 year	na		na		na		na
By 3 years	0.96 [0.57–1.62]	0.04	1.00 [0.99–1.01]	0.74	0.99 [0.57–1.74]	0.63	1.00 [0.99–1.01]	0.51

*OR, odds ratio; CI, confidence interval.

^†Adjusted for maternal age, pre‐pregnancy maternal BMI, tobacco use during pregnancy, exposure of the child to environmental tobacco smoke (from birth to 3 years of age), residence in damp housing (from birth to 3 years of age), maternal atopy, the child's gender, the season of birth, birthweight, exclusive breastfeeding for at least 4 months, the number of older siblings, the mother's educational level, and the household income; na: data not available.

^§ p, p‐value.