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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: J Immunol. 2017 Jan 27;198(5):1995–2005. doi: 10.4049/jimmunol.1601425

Figure 7. Cluster analysis of DEGs and DIGs with serological and immunological correlates of TIV response.

Figure 7

Heatmap showing pairwise Spearman correlations for a group of parameters including 33 DEGs and DIGs and 9 serological and immunological correlates were calculated against each other using R statistical software. Spearman correlations that resulted in p-value >0.05 were assigned an r-value of 0 (white), while significant correlations were clustered and visualized as a heatmap depicting r-values on a scale of −1 (pink) to 1 (green). The parameters tested are color-coded as follows: blue font designates parameters from Non-pTfh cells, green from CD4 T cells, red from pTfh cells, and black font designates Serum Titer and Elispot results for each vaccine antigen.