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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Neuroimage. 2016 Nov 5;146:1050–1061. doi: 10.1016/j.neuroimage.2016.10.049

Figure 2.

Figure 2

Functional activation maps of CBV modulation by SNr- and GPe-DBS. Two DBS stimulation frequencies are shown for each target: SNr- DBS at 40 or 130 Hz (A and B, respectively), GPe-DBS at 40 or 130 Hz (C and D, respectively). Notable observations include CBV decreases in the striatum at both targets, as well as large, ipsilateral frontal cortical modulation by GPe-DBS. At both targets, stimulation responses were largely ipsilateral and stronger at 130 Hz compared to 40 Hz. 12 slices were acquired in each scan, with numbers below slices denoting relative distance from bregma (in mm). Color bar denotes t score values obtained by GLM analyses, with a significance threshold of p < 0.05. Functional activation maps for all additional tested frequencies are located in Supplemental Figures S4–5.