Table 3.
Antibiotic resistance profiles and genotypes in MLST of eighty K. pneumoniae isolates from bloodstream infections.
| ST | Antibiotic resistance profiles | Resistance determinants | Number of isolates |
|---|---|---|---|
| ST1 | CAZ-CRO-FEP-CTX-CXM-TOB-PRL-ATM-CIP-LEV-SAM-TZP-IPM-MEM-SXT | – | 1 |
| ST2 | - | – | 1 |
| ST6 | CAZ-CRO-FEP-CTX-CXM-PRL-ATM-SAM-TZP | SHV-1 | 1 |
| ST11 | CAZ-CRO-CTX-CXM-TOB-PRL-ATM-CIP-LEV-SAM-SXT | SHV-11 | 1 |
| CAZ-CRO-FEP-CTX-CXM-AK-CN-TOB-PRL-ATM-CIP-LEV-SAM-TZP-IPM-MEM | KPC-2 | 3 | |
| CAZ-CRO-FEP-CTX-CXM-AK-CN-TOB-PRL-ATM-CIP-LEV-SAM-TZP-IPM-MEM | TEM-1, SHV-11, CTX-M-14, KPC-2 | 1 | |
| CAZ-CRO-FEP-CTX-CXM-AK-CN-TOB-PRL-ATM-CIP-LEV-SAM-TZP-IPM-MEM-SXT | KPC-2 | 6 | |
| CAZ-CRO-FEP-CTX-CXM-AK-CN-TOB-PRL-ATM-CIP-LEV-SAM-TZP-MEM | – | 1 | |
| CAZ-CRO-FEP-CTX-CXM-CN-PRL-ATM-CIP-LEV-SAM-TZP-IPM-MEM-SXT | KPC-2 | 1 | |
| CAZ-CRO-FEP-CTX-CXM-CN-PRL-ATM-CIP-LEV-SAM-TZP-IPM-MEM-SXT | SHV-12, CTX-M-14, KPC-2 | 1 | |
| CAZ-CRO-FEP-CTX-CXM-TOB-PRL-ATM-CIP-LEV-SAM-TZP-IPM-MEM | |||
| ST15 | CAZ-CRO-FEP-CTX-CXM-AK-CN-TOB-PRL-ATM-CIP-LEV-SAM-IPM-SXT | SHV-1, CTX-M-14 | 1 |
| CAZ-CRO-FEP-CTX-CXM-CN-TOB-PRL-ATM-CIP-LEV-SAM-TZP-SXT | SHV-12 | 1 | |
| CAZ-CRO-FEP-CTX-CXM-CN-TOB-PRL-ATM-CIP-SAM-SXT | TEM-1, SHV-1, CTX-M-15 | 1 | |
| CAZ-CRO-FEP-CTX-CXM-CN-TOB-PRL-ATM-CIP-SAM-TZP-SXT | TEM-1, SHV-12, CTX-M-15 | 1 | |
| CIP-LEV-SAM-SXT | – | 2 | |
| CRO-CTX-CXM-PRL-ATM-CIP-LEV-SAM-SXT | SHV-1 | 1 | |
| ST23 | – | – | 3 |
| ST26 | CRO-CTX-CXM-PRL-SAM-SXT | SHV-28 | 1 |
| ST29 | – | – | 2 |
| CXM-SAM | – | 2 | |
| ST35 | CTX-CXM-CN-PRL-SXT | – | 1 |
| CAZ-CRO-FEP-CTX-CXM-CN-TOB-PRL-ATM-CIP-SAM-SXT | TEM-1, SHV-33, CTX-M-15 | 1 | |
| ST37 | CRO-CXM-CN-PRL-SXT | – | 1 |
| CAZ-CXM-TOB-PRL-CIP-LEV-SAM-SXT | – | 1 | |
| ST45 | – | – | 1 |
| ST60 | – | – | 1 |
| ST65 | – | – | 1 |
| ST86 | CXM-SAM | – | 1 |
| CXM-SXT | – | 1 | |
| ST107 | CRO-FEP-CTX-CXM-CN-PRL-ATM-SAM-SXT | SHV-36, CTX-M-14 | 2 |
| ST218 | – | – | 1 |
| ST231 | CRO-FEP-CTX-CXM-CN-PRL-ATM-CIP-LEV-SAM-SXT | TEM-1, SHV-1, CTX-M-65 | 1 |
| ST245 | – | – | 1 |
| ST252 | – | – | 1 |
| ST290 | CRO-CTX-CXM-CN-PRL-SAM-SXT | TEM-103, SHV-1, CTX-M-65 | 1 |
| ST307 | CAZ-CRO-FEP-CTX-CXM-AK-CN-TOB-PRL-ATM-CIP-LEV-SAM-TZP-SXT | TEM-1, SHV-1, CTX-M-15 | 1 |
| ST340 | CRO-FEP-CTX-CXM-PRL-ATM-CIP-LEV-SAM-TZP-MEM-SXT | – | 1 |
| ST347 | – | – | 1 |
| ST367 | – | – | 1 |
| ST374 | – | – | 1 |
| ST380 | – | – | 1 |
| ST397 | CRO-FEP-CTX-CXM-CN-TOB-PRL-ATM-CIP-SAM-SXT | TEM-1, SHV-1, CTX-M-15 | 1 |
| ST412 | – | – | 1 |
| ST485 | – | – | 2 |
| ST628 | CRO-CTX-CXM-CN-PRL-SXT | SHV-1, CTX-M-14 | 1 |
| CRO-CTX-CXM-CN-PRL-CIP-LEV-SAM-SXT | SHV-1, CTX-M-14 | 1 | |
| CRO-CTX-CXM-CN-PRL-SXT | SHV-1, CTX-M-65 | 1 | |
| ST629 | CRO-CTX-CXM-CN-TOB-PRL | SHV-11, CTX-M-65 | 1 |
| ST685 | CIP-LEV-SXT | – | 1 |
| ST788 | – | – | 1 |
| ST948 | – | – | 1 |
| ST1023 | CXM-AK-CN-TOB-PRL-CIP-SAM-SXT | – | 1 |
| ST1118 | SXT | – | 1 |
| ST1333 | – | – | 2 |
| ST1440 | – | – | 1 |
| ST1465 | CAZ-CRO-FEP-CTX-CXM-AK-CN-TOB-PRL-ATM-CIP-SAM-SXT | TEM-1, SHV-12, CTX-M-15 | 1 |
| ST1545 | – | – | 2 |
| ST1712 | CRO-FEP-CTX-CXM-CN-PRL-ATM-CIP-SAM-SXT | – | 1 |
| ST1765 | CAZ-CRO-FEP-CTX-CXM-AK-CN-TOB-PRL-ATM-SAM-TZP | – | 1 |
| ST1779 | PRL-SAM | – | 1 |
| ST1887 | SXT | – | 1 |
| ST2247 | – | – | 1 |
| ST2248 | – | – | 1 |
| ST2249 | – | – | 1 |
CAZ, ceftazidime; CRO, ceftriaxone; FEP, cefepime; CTX, cefotaxime; CXM, cefuroxime; AK, amikacin; CN, gentamicin; TOB, tobramycin; PRL, piperacillin; ATM, aztreonam; CIP, ciprofloxacin; LEV, levofloxacin; SAM, ampicillin-sulbactam; TZP, piperacillin-tazobactam; IPM, imipenem; MEM, meropenem; SCF, cefoperazone-sulbactam; SXT, trimethoprim-sulfamethoxazole.