Table 2.
Results of PERMANOVA and ANOSIM comparing the fecal microbiota of C57BL/6Hsd donors or C57BL/6J recipients prior to fecal microbiota transfer (FMT) and the same C57BL/6J recipients 1 week (1 w), 2 weeks (2 w), and 4 weeks (4 w) post-FMT using fresh feces, frozen feces, or fresh cecal contents as the source material for FMT.
| Comparison | PERMANOVA | ANOSIM | |||
|---|---|---|---|---|---|
| p-values | F-values | p-values | R-values | ||
| B6/Hsd DONORS AND B6/J RECIPIENTS | |||||
| Donor feces (n = 25) | Recipient feces 1 w post-FMT using fresh feces (n = 8) | 0.0015 | 9.53 | 0.0249 | 0.202 |
| Recipient feces 2 w post-FMT using fresh feces | 0.003 | 7.64 | 0.0146 | 0.2091 | |
| Recipient feces 4 w post-FMT using fresh feces | 0.0041 | 6.204 | 0.0006 | 0.3327 | |
| Donor feces (n = 25) | Recipient feces 1 w post-FMT using frozen feces (n = 6) | 0.3974 | 0.8281 | 0.1372 | 0.1093 |
| Recipient feces 2 w post-FMT using frozen feces | 0.0665 | 3.066 | 0.0176 | 0.2295 | |
| Recipient feces 4 w post-FMT using frozen feces | 0.0056 | 5.975 | 0.0042 | 0.3335 | |
| Donor feces (n = 25) | Recipient feces 1 w post-FMT using cecal contents (n = 8) | 0.1296 | 2.001 | 0.1905 | 0.07034 |
| Recipient feces 2 w post-FMT using cecal contents | 0.0574 | 2.96 | 0.1226 | 0.1098 | |
| Recipient feces 4 w post-FMT using cecal contents | 0.0228 | 4.158 | 0.019 | 0.2051 | |
| Recipient feces pre-FMT(n = 22) | Recipient feces 1 w post-FMT using fresh feces (n = 8) | 0.0001 | 14.31 | 0.0005 | 0.4912 |
| Recipient feces 2 w post-FMT using fresh feces | 0.0001 | 13.89 | 0.0003 | 0.5214 | |
| Recipient feces 4 w post-FMT using fresh feces | 0.0002 | 20.53 | 0.0001 | 0.7167 | |
| Recipient feces pre-FMT (n = 22) | Recipient feces 1 w post-FMT using frozen feces (n = 6) | 0.0019 | 8.308 | 0.0002 | 0.5629 |
| Recipient feces 2 w post-FMT using frozen feces | 0.0007 | 12.31 | 0.0001 | 0.6443 | |
| Recipient feces 4 w post-FMT using frozen feces | 0.0002 | 16.55 | 0.0001 | 0.6932 | |
| Recipient feces pre-FMT (n = 22) | Recipient feces 1 w post-FMT using cecal contents (n = 8) | 0.0002 | 12.4 | 0.0001 | 0.5983 |
| Recipient feces 2 w post-FMT using cecal contents | 0.0001 | 15.77 | 0.0001 | 0.6337 | |
| Recipient feces 4 w post-FMT using cecal contents | 0.0001 | 16.48 | 0.0001 | 0.6046 | |
Significant p-values indicated in bold.