Table 3.
Results of PERMANOVA and ANOSIM comparing the fecal microbiota of C57BL/6J donors or C57BL/6Hsd recipients prior to fecal microbiota transfer (FMT) and the same C57BL/6Hsd recipients 1 week (1 w), 2 weeks (2 w), and 4 weeks (4 w) post-FMT using fresh feces, frozen feces, or fresh cecal contents as the source material for FMT.
PERMANOVA | ANOSIM | ||||
---|---|---|---|---|---|
p-values | F-values | p-values | R-values | ||
B6/J DONORS AND B6/Hsd RECIPIENTS | |||||
Donor feces (n = 24) | Recipient feces 1 w post-FMT using fresh feces (n = 8) | 0.0004 | 9.626 | 0.0001 | 0.5059 |
Recipient feces 2 w post-FMT using fresh feces | 0.0004 | 10.6 | 0.0002 | 0.5378 | |
Recipient feces 4 w post-FMT using fresh feces | 0.0001 | 12.47 | 0.0002 | 0.5522 | |
Donor feces (n = 24) | Recipient feces 1 w post-FMT using frozen feces (n = 8) | 0.0001 | 17 | 0.0001 | 0.7224 |
Recipient feces 2 w post-FMT using frozen feces | 0.0001 | 25.23 | 0.0001 | 0.7361 | |
Recipient feces 4 w post-FMT using frozen feces | 0.0001 | 22.98 | 0.0001 | 0.7342 | |
Donor feces (n = 24) | Recipient feces 1 w post-FMT using cecal contents (n = 9) | 0.0001 | 15.56 | 0.0001 | 0.6982 |
Recipient feces 2 w post-FMT using cecal contents | 0.0001 | 21.41 | 0.0001 | 0.7943 | |
Recipient feces 4 w post-FMT using cecal contents | 0.0001 | 16.71 | 0.0001 | 0.7136 | |
Recipient feces pre-FMT (n = 25) | Recipient feces 1 w post-FMT using fresh feces (n = 8) | 0.1411 | 1.945 | 0.3223 | 0.03354 |
Recipient feces 2 w post-FMT using fresh feces | 0.0889 | 2.549 | 0.0832 | 0.1204 | |
Recipient feces 4 w post-FMT using fresh feces | 0.0481 | 3.045 | 0.0277 | 0.2002 | |
Recipient feces pre-FMT (n = 25) | Recipient feces 1 w post-FMT using frozen feces (n = 8) | 0.0073 | 5.056 | 0.0035 | 0.2973 |
Recipient feces 2 w post-FMT using frozen feces | 0.0055 | 6.873 | 0.0012 | 0.335 | |
Recipient feces 4 w post-FMT using frozen feces | 0.0003 | 10.71 | 0.0001 | 0.5049 | |
Recipient feces pre-FMT (n = 25) | Recipient feces 1 w post-FMT using cecal contents (n = 9) | 0.0001 | 10.48 | 0.0001 | 0.5381 |
Recipient feces 2 w post-FMT using cecal contents | 0.0001 | 10.14 | 0.0001 | 0.5573 | |
Recipient feces 4 w post-FMT using cecal contents | 0.0001 | 8.241 | 0.0001 | 0.4945 |
Significant p-values indicated in bold.