Table 2. Structural parameters of distal femur trabecular bone in newborn mice.
| BV/TV (%) | Tb.Th (mm) | Tb.Sp (mm) | Tb.N (1/mm) | SMI | |
|---|---|---|---|---|---|
| newborn | |||||
| WT (n = 3) | 43.16 ± 1.85 | 0.076 ± 0.007 | 0.086 ± 0.006 | 5.718 ± 0.35 | 1.487 ± 0.24 |
| ACH/ACH (n = 3) | 15.76 ± 3.93*** | 0.058 ± 0.011 | 0.17 ± 0.045 | 2.74 ± 0.71*** | 2.436 ± 0.26** |
| 1 year old | |||||
| WT (n = 4) | 5.22 ± 0.51 | 0.079 ± 0.010 | 0.383 ± 0.047 | 0.661 ± 0.087 | 2.569 ± 0.20 |
| ACH/ACH (n = 3) | 2.74 ± 1.08* | 0.069 ± 0.003 | 0.378 ± 0.075 | 0.402 ± 0.169 | 2.87 ± 0.37 |
WT: wild-type littermates; ACH/ACH: FGFRACH/ACH mice. BV/TV: trabecular bone volume/tissue volume; Th.Th: trabecular thickness; Th.Sp: trabecular separation; Tb.N: trabecular number; SMI: structure model index. Each value is expressed as the mean ± SD (all groups n = 3). *p < 0.05; ***p < 0.01; ***p < 0.001.