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. 2017 Feb 23;7:43137. doi: 10.1038/srep43137

Figure 5.

Figure 5

Effects of the selective noradrenergic α-adrenoceptor antagonist phentolamine (A,B), β-adrenoceptor antagonist propranolol (C,D), α1-adrenoceptor antagonist prazosin, α2-adrenoceptor receptor antagonist yohimbe, and the mixture of the μ-opioid receptor antagonist CTAP and yohimbe (E), given intrathecally, on dezocine and morphine antinociception in neuropathic rats, induced by tight ligation of L5/L6 spinal nerves. Data are presented as means ± SEM (n = 6 in each group). *P < 0.05 vs. the normal saline control or respective normal saline + dezocine and normal saline + morphine group, by repeats-measured two-way ANOVA followed by post-hoc student-Newman-Keuls tests.