Table 1.
Effect of HPE-XA-08 on blood biochemicals related to liver damage (ALT, AST, ALP, and GGT) for observation of protective activity.
| Group | ALT (IU/L) | AST (IU/L) | ALP (IU/L) | GGT (IU/L) |
|---|---|---|---|---|
| Normal saline + H2O (1P) | 80.00 ± 4.175 | 237.3 ± 12.84 | 173.6 ± 7.807 | 2.286 ± 0.4206 |
| Normal saline + HPE-XA-08 (2P)# | 76.00 ± 4.416 | 223.3 ± 11.16 | 170.3 ± 23.68 | 3.750 ± 0.4787 |
| TAA + H2O (3P) | 88.50 ± 12.75 | 215.0 ± 13.64 | 375.0 ± 10.41∗ | 37.50 ± 1.857∗ |
| TAA + HPE-XA-08 (4P)+ | 69.40 ± 7.756 | 222.4 ± 5.715 | 277.0 ± 4.722 | 30.80 ± 3.980 |
∗Levels of enzymes between 1P and 3P were compared to show the effects of TAA on the level of liver enzymes; ∗ indicates p < 0.05.
#Levels of enzymes between 1P and 2P were compared to show the effects of HPE-XA-08 on the level of liver enzymes but did not show statistically significant value (p > 0.05).
+Levels of enzymes between 3P and 4P were compared to show the effects of HPE-XA-08 on preventing TAA-induced liver cirrhosis but did not show statistically significant value (p > 0.05).