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. Author manuscript; available in PMC: 2017 Feb 23.
Published in final edited form as: Curr Biol. 2016 Nov 7;26(21):R1150–R1152. doi: 10.1016/j.cub.2016.09.026

Figure 1. Molecular models for the cytokinesis-node assembly and architecture.

Figure 1

(A)Model for cytokinesis-node assembly based on spinning disk confocal microscopy. Proteins are assembled hierarchically into nodes (left), which eventually capture and pull actin filaments to condense (right). Time 0 is defined as the initiation of mitosis when spindle pole bodies separate. Republished with permission of Rockefeller University Press, from [10], permission conveyed through Copyright Clearance Center, Inc. (B,C) Structure of cytokinesis nodes in a side view (B) and a face view from the top of the cell (C) with (right) and without (left) actin filaments. Reproduced from [3] © 2016 National Academy of Sciences, USA.