Table 4.
The allele-specific copy number (ASCN) of the 11 genes with high loss of heterozygosity (LOH) frequency
| Gene symbol | The copy number of A allele | The copy number of B allele | Proportion (%) | Description | Log2 FC |
|---|---|---|---|---|---|
| LXN | 2 | 0 | 100 | Loss of the one allele,gain of another allele | −1.9225 |
| RASL11A | 2 | 0 | 100 | Loss of the one allele,gain of another allele | −0.885 |
| KCNRG | 0 | 2 | 100 | Loss of the one allele,gain of another allele | −0.6275 |
| TFAP2C | 0.3 | 1.7 | 70 | Copy neutral LOH in 70% | 0.9875 |
| SPHK1 | 0.3 | 1.7 | 70 | Copy neutral LOH in 70% | 0.6825 |
| TP53INP1 | 1.6 | 0.4 | 60 | Copy neutral LOH in 60% | −0.795 |
| HOXD12 | 1.5 | 0.5 | 50 | Copy neutral LOH in 50% | 0.87 |
| ERRFI1 | 1.5 | 0.5 | 50 | Copy neutral LOH in 50% | −1.195 |
| RPS6KA6 | 0.6 | 1.6 | 50 | Loss of one allele in 50% | −1.12 |
| DNAJB4 | 0.4 | 1.4 | 50 | Copy neutral LOH in 50% | −1.02 |
| ITGA7 | 0.5 | 1.5 | 50 | Copy neutral LOH in 50% | −0.925 |
Gene symbol the name of one gene, proportion the percentage of copy number of A allele minus copy number of B allele, Description the frequency of LOH, FC fold change