Table 5.

Function annotation of differentially expressed genes (DEGs) in carcinoma-associated fibroblasts (CAF)

	TF genes	Oncogenes	TSG
Up-regualted	RUNX3, MEOX2, FOXE1, HOXD12, TFAP2C, ID1	SPHK1	RUNX3
Down-regulated	TBX4, RORB, PPARG, KLF4, IFI16, PBX1, SOX5, NFIA, SMAD3, FOXP2	TEC, MLF1, PBX1, BANF, MLLT3,CDON	LXN, DPP4, CLU, RARRES1, TGFBI, IGFBP5, ERRFI1, CADM1, JUP, DIRAS3, TXNIP, RARRES3, RPS6KA6, DNAJB4, WNT5A, SFRP1, ITGA7, DAPK1, RASL11A, EPB41, TP53INP1, SCARA3, HBP1, LIMD1, FBXO32, SMAD3, RNASET2, KCNRG, SEMA3B, NRCAM

TF transcription factor, TSG tumor suppressor gene